Publications de 2002 à 2006

Publications scientifiques 2006

1. Impact of the interaction between Herpes Simplex Virus type 1 regulatory ICPO and ubiquitin specific protease USP7 on the activation on adeno-associated Virus type 2 rep gene expression.
Geoffroy M.C, Chadeuf G, Orr A, Salvetti A and Everett R.
J Virol 80(7) :3650-4

2. Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors.
Stieger K, Le Meur G, Lasne F, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Martin L, Moullier P, Rolling F.
Mol Ther13(5) :967-75

3. Gene Therapy of the brain in the dog model of Hurler’s syndrome.
Ciron C, Desmaris N, Colle MA, Raoul S, Joussemet B, Verot L, Ausseil J, Froissart R, Roux F, Cherel Y, Ferry N, Lajat Y, Schwartz B, Vannier MT, Maire I, Tarideu M, Moullier P, Heard JM.
Ann Neurol.2006 Aug ;60(2) :204-13

4. Proteolytic Mapping of the adeno-associated virus capsid.
Kim Van Vliet and Veronique Blouin, Mavis Agbandje-McKenna, Richard O.Snyder.
Mol Ther.2006 dec ;14(6) :809-21

5. Gene therapeutic prospects in early onset of severe retinal dystrophy : restoration of vision in RPE65 Briard dogs using an AAv serotype 4 vector that specifically targets the retinal pigmented epithelium.
Rolling F, Le Meur G, Stieger K, Smith AJ, Weber M, Deshamps JY, Nivard D, Mendes- Madeira A, Provost N, Pereon Y, Cherel Y, Ali RR, Hamel C, Moullier P.
Bull Mem Acad R Med Belg. 2006 ;161(10-12) :497-508

Publications scientifiques 2005

1. Biodistribution of rAAV vectors following intraocular administration : evidence for the presence and persistence of vector DNA in the optic nerve and in the brain.
Provost N., Le Meur G., Weber M., Mendes-Madeira A., Podevin G., Cherel Y., Colle MA, Deschamps JY, Moullier P., Rolling F.
Mol Ther 11(2):275-83.

2. Postsurgical assessment and long term safety of recombinant adeno-associated virus-mediated gene transfer into the retinas of dogs and primates.
Le Meur G., Weber M., Pereon Y., Mendes-Madeira A., Nivard D., Deschamps JY, Moullier M., Rolling F.
Arch. Ophthalmol. 123:500-506.

3. Intracellular route and biological activity of exogenously delivered Rep proteins from the adeno-associated virus.
Awedikian R., François A., Guilbaud M., Moullier P., Salvetti A.
Virology. 335(2) :252-263.

4. Evidence for encapsidation of prokaryotic sequences during rAAV production and their in vivo persistence after vector delivery.
Chadeuf G., Ciron C., Moullier P., Salvetti A.
Mol. Ther. Oct ;12(4) :744-53.

5. In vivo gene transfer to the rat retina using herpes simplex virus type 1 (HSV-1)-based amplicon vectors.
Fraefel C., Mendes-Madeira A., Mabon O., Lefevre A., Le Meur G., Ackermann M., Moullier P., Rolling F.
Gene Ther. 12(16):1283-1288

6. The cellular TATA binding protein is required for Rep-dependent replication of a minimal adeno-associated virus type 2 p5 element.
Francois A., Guilbaud M., Awedikian R., Chadeuf G., Moullier P., Salvetti A.
J. Virol. 79(17):11082-11094

7.Adeno-associated viral vectors for retinal gene transfer and treatment of retinal diseases.
Auricchio A, Rolling F.
Curr Gene Ther 5(3) :339-48

8. Helper functions required for wild type and recombinant adeno-associated virus growth.
Geoffroy M.C, Salvetti A.
Current Gene Therapy 12(4) : 744-53

9. The Twelfth annual meeting of European Society of Gene Therapy.
Grez M, Galun E, Moullier P.
Mol Ther. 2005 Feb ;11(2) :178-9

10. Gene therapy of the brain in the dog model of Hurler's syndrome.
Ciron C, Desmaris N, Colle MA, Raoul S, Joussemet B, Vérot L, Ausseil J, Froissart R, Roux F, Chérel Y, Ferry N, Lajat Y, Schwartz B, Vanier MT, Maire I, Tardieu M, Moullier P, Heard JM.
Ann Neurol. 2006 Aug;60(2):204-13.

11. Tetracycline-inducible viral interleukin-10 intraocular gene transfer, using adeno-associated virus experimental autoimmune uveoretinitis.
Smith JR, Verwaerde C., Rolling F., Naud MC, Delanove A., Thillaye-Goldenberg B., Apparailly F., de Kozak Y.
Hum Gene Ther. 16(9) :1037-1046.

Publications scientifiques 2004

1. Autoimmune anemia in macaques following erythropoietin gene therapy.
Chenuaud P ., Larchet T., Rabinowitz JE, Provost N., Cherel Y., Casadevall N., Samulski RJS, Moullier P.
Blood. 103(9) :3303-3304.

2. Optimal design of a single recombinant adeno-associated virus derived from serotypes 1 and 2 to achieve more tightly regulated transgene expression from nonhuman primate muscle.
Chenuaud P ., Larcher T., Rabinowitz JE, Provost N., Joussemet B., Bujard H., Samulski RJS, Favre D., Moullier P.
Mol. Ther. 9 :410-418

3. Factors influencing immune response after in vivo retrovirus-mediated gene transfer to the liver.
Podevin G., Otta E ;, Nguyen JM, Pichard V., Aubert D., Moullier P., Ferry N.
J Gene Med. 6(1) :16-21

4. Identification of a replication-defective herpes simplex virus for recombinant adeno-associated virus type 2 (rAAV2) particle assembly using stable producer cell lines.
Toublanc E, Benraiss A, Bonnin D, Blouin V, Brument N, Cartier N, Epstein AL, Moullier P, Salvetti A.
J. Gene Med. 6(5) :555-564

5. Improving rAAV production and purification : towards the definition of a scaleable process.
Blouin V, Brument N, Toublanc E, Raimbaud I, Moullier P, Salvetti A.
J Gene Med. 2004. 6:S223-S228.

6. Early detection of a two-long-terminal-repeat junction molecule in the cytoplasm of recombinant murine leukemia virus-infected cells.
Serhan F., Penaud M., Petit C., Leste-Lasserre T.,Trajcevski S., Klatzmann D. Duisit G., Sonigo P., Moullier P.
J. Virol. 78(12) :6190-6199.

7. The herpes simplex virus type 1 ICP0 protein mediates the activation of adeno-associated virus type 2 rep gene expression from a latent integrated form.
Geoffroy MC, Epstein AL, Toublanc E., Moullier P., Salvetti A.
J. Virol. 78(20) :10977-10986.

8. Recombinant AAV-mediated gene transfer to the retina : gene therapy perspectives.
Rolling F.
Gene Ther.11 :S26-S32.

9.« Genetic doping” with erythropoietin cDNA in primate muscle is detectable.
Lasne F., Martin L., de Ceaurriz J., Larcher T., Moullier P., Chenuaud P.
Mol. Ther. 10(3) 409-410.

10. AAV gene transfer to the retina does not protect retrovirally transduced hepatocytes from the immune response.
Bellodi-Privato M, Le Meur G, Aubert D, Mendes-Madera A, Pichard V, Rolling F, Ferry N.
J Mol Med.;82(6):403-10.

11. La Génétique.
Fabre-Magnan M., Moullier P.
Science Humaine. Collection « Débats ». Editions Belin. Avril 2004

Publications scientifiques 2003

Publications scientifiques 2002

1. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity.
Rabinowitz JE, Rolling F., Li C., Conrath H., Xiao W., Xiao X., Samulski RJS.
J. Virol 76 :791-801

2. Cytotoxic immune response blunts long term transgene expression after efficient retroviral-mediated hepatic gene transfer in rat.
Aubert D., Ménoret S., Chiari E., Pichard V., Durand S., Tesson L., Moullier P., Anegon I., Ferry N.
Mol. Ther. 5:388-396.

3.Recombinant adeno-associated virus type 2 mediates highly efficient gene transfer in regenerating rat skeletal muscle.
Abadie J., Blouin V., Guigand L., Wyers M., Cherel Y.
Gene Ther. 9(15):1037-43.

4. Five recombinant simian immunodeficiency virus (SIV) pseudotypes lead to exclusive transduction of retinal pigmented epithelium in rat.
Duisit G., Conrath H., Saleun S., Folliot S., Provost N., Cosset F.-L., Sandrin V., Moullier P., Rolling F..
Mol. Ther. 6(4) :446-454

5. Characterization of a Producer Cell-Dependent Restriction of MLV Replication.
Serhan F., Jourdan N., Saleun S., Moullier P., Duisit G.
J. Virol. 76:6609-6617.

6. Liver regeneration: with help from marrow.
Ferry N., Hadchouel M.
J. Hepatol. 36:695-697.

7. Lack of immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.
Favre D., Blouin V., Provost N., Spisek R., Porrot F., Bohl D., Marmé F., Chérel Y., Salvetti A., Hurtrel B., Heard J.-M., Rivière Y., Moullier P.
J. Virol. 76(22) 11605-11611

8. A versatile and scalable two-step ion-exchange chromatography process for the purification of recombinant adeno-associated virus serotypes –2 and –5.
Brument N., Morenweiser R., Blouin V., Toublanc E., Raimbaud I., Chérel Y., Folliot S., Gaden F., Boulanger P., Kroner-Lux G., Moullier P., Rolling F., Salvetti A.
Mol. Ther. 6:678-686.

9. Differential sensitivity of endothelial cells of various species to apoptosis induced by gene transfer of Fas ligand: role of FLIP levels.
Bouchet D., Tesson L., Ménoret S., Charreau B., Mathieu P., Yagita H., Duisit G., Anegon I.
Mol. Med. 8(10) ;612-623

10. In vivo cell lineage analysis during chemical hepatocarcinogenesis in rats using retroviral mediated gene transfer : Evidence for dedifferentiation of mature hepatocytes.
Gournay J., Auvigne I., Pichard V., Ligeza C., Bralet M.-P., Ferry N.
Lab. Invest 82(6):781-8.

11. LacZ transgenic rats tolerant for beta-galactosidase: recipients for gene transfer studies using lacZ as reporter gene.
Menoret S., Aubert D., Tesson L., Braudeau C., Pichard V., Ferry N., Anegon I.
Hum. Gene Ther. 13(11):1383-1390.

12. Demonstration of direct lineage between hepatocytes and hepatocellular carcinoma in diethylnitrosamine-treated rats.
Bralet MP, Pichard V., Ferry N.
Hepatology 36(3):623-630.

13. Lentiviral vectors derived from simian immunodeficiency virus.
Negre D., Duisit G., Mangeot PE, Moullier P., Darlix JL., Cosset FL.
Curr Top Microbiol Immunol. 261:53-74

14. In vivo study of mitogenic and tumor initiating effects of cyproterone acetate using cell lineage analysis of genetically labeled hepatocytes.
Auvigne I., Pichard V., Aubert D., Robillard N., Ferry N.
Hepatology . 35(2):281-288

Mis à jour le 29 mars 2018.